UF College of Medicine celebrates 48th annual Medical Guild Research Symposium
Rachel Newsome won gold for her work on intestinal microbes and lung cancer therapy
April 18, 2023 — In a world of rapid discovery and perplexing health care mysteries, doctoral students in the University of Florida College of Medicine’s Graduate Program in Biomedical Sciences are making an impact as they tackle today’s biggest medical questions.
Eight graduate students presented their thesis research to an audience of peers, mentors and colleagues during the 48th annual Medical Guild Research Symposium on April 12 in the George T. Harrell, M.D., Medical Education Building. Competing for bronze, silver and gold prizes of $1,000-$2,500 endowed by the UF Medical Guild Inc., each student represented their biomedical sciences concentration to a panel of faculty judges. Their research explored new therapies, imaging techniques and analyses of complex and deadly conditions, like diabetes, metastatic cancer and hypertension.
“This is a great opportunity to showcase our next-generation scientists,” said College of Medicine Dean Colleen Koch, M.D., M.S., M.B.A., to the symposium audience. “You can really see their research in action. I’d also like to express my gratitude to the Medical Guild. Your support over the years has been incredible.”
Thomas Rowe, Ph.D., director of the Graduate Program in Biomedical Sciences and associate dean for graduate education, said the annual symposium is an inspiration to faculty mentors and students alike.
“You can’t help but feel great knowing this is the future of the biomedical sciences field,” he said. “It’s remarkable how sophisticated they’ve become and how creatively they’re thinking.”
This year, a new award was added to the competition to recognize one additional student whose work was outstanding in the earlier competition rounds. Natalie Johnson, a graduate researcher in the pharmacology and therapeutics concentration, received the inaugural Honorable Mention Award.
Rachel Newsome, a UF undergraduate alumna and fifth-year doctoral candidate in the cancer biology concentration, took home the gold prize for her research targeting the gut microbiome in lung cancer patients to improve their immune response. She plans to use a portion of her winnings to throw a pizza party for her lab. And after graduating later this year, Newsome said, she and her mentor, Christian Jobin, Ph.D., a tenured professor of medicine and program leader of cancer microbiota and host response at the UF Health Cancer Center, want to start a company based on the microbiome therapy.
“We’re hoping to apply it to colorectal cancer and brain cancer with potential for all cancers,” Newsome said. “I’m very surprised but very honored to receive the gold award. Everyone who presented was really amazing.”
List of winners
Gold
- Rachel Newsome, cancer biology, mentored by Christian Jobin, Ph.D., “Microbial-derived immunostimulatory small molecules synergize with anti-PD-1 therapy in lung cancer”
Silver
- Mario Chang, biochemistry and molecular biology, mentored by Matthew Merritt, Ph.D., “Assessing chemotherapeutic efficacy in vivo using deuterium metabolic imaging”
- Caitlin Baumer-Harrison, physiology and functional genomics, mentored by Annette De Kloet, Ph.D., “Alleviating hypertension through modulation of specific vagal nerves”
- Cora Hart, pharmacology and therapeutics, mentored by Lee Sweeney, Ph.D., “Getting to the heart of DMD”
- Grace Lloyd, neuroscience, mentored by Benoit Giasson, Ph.D., “Strain diversity in synucleinopathies”
Bronze
- Mollie Huber, immunology and microbiology, mentored by Mark Atkinson, Ph.D., “Declines in B cell function and glucose responsiveness are independent of insulitis during T1D pathogenesis”
- Sadia Sarwar, molecular cell biology, mentored by Alexander Ishov, Ph.D., “Exploring novel chemotherapeutic interventions to overcome taxane therapy resistance in castration resistant prostate cancer (CRPC)”
- Frederick Ashby, genetics, mentored by Coy Heldermon M.D., Ph.D., “Transduction efficiency of 19 barcoded AAV capsid variants within Sanfilippo Syndrome type-B C57/BL6 mice compared to wild-type”
Honorable Mention
Natalie Johnson, pharmacology and therapeutics, mentored by Daniel Wesson, Ph.D.
2022-23 Doctoral Mentoring Awards
- Eric Wang, Ph.D., genetics
- Robert McKenna, Ph.D., biochemistry and molecular biology
Council of Academic Chairs Scholarship
- Mario Chang, biochemistry and molecular biology, mentored by Matthew Merritt, Ph.D.
Advancement to Candidacy Award
- Mario Chang, biochemistry and molecular biology, mentored by Matthew Merritt, Ph.D.
- Zane Moreland, pharmacology and therapeutics, mentored by Jonathan Bird, Ph.D.
- Samantha Smith, neuroscience, mentored by Sara Burke, Ph.D.
Education Initiative Award
- Natalie Johnson, pharmacology and therapeutics, mentored by Daniel Wesson, Ph.D.